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Collagen Stimulators

Biostimulators that rebuild the skin’s own collagen: polylactic acid (Sculptra, Fize PLA) and calcium hydroxylapatite (Radiesse, Urevs 4D Fill). Genuine stock for UK clinics at trade prices, dispatched from London. Guides: Sculptra vs Radiesse and Radiesse and hyperdilution.

Showing all 7 results

  • Sculptra 1 vial (5 ml)

    Sculptra 1 vial (5 ml)

    £119.99

    In stock · next-day delivery

    Pack 1 vial, for reconstitution to 5 ml
    Lidocaine No
    Country of origin Sweden
    Needles Not included
  • Sculptra box (2 vials)

    Sculptra box (2 vials)

    £214.99

    In stock · next-day delivery

    Pack Box of 2 vials, instructions and 2 patient and practitioner labels (1 per vial, on the pack)
    Lidocaine No
    Country of origin Sweden
    Needles Not included
  • Radiesse (1 x 1.5 ml)

    Radiesse (1 x 1.5 ml)

    £118.80

    In stock · next-day delivery

    Pack 1 x 1.5 ml syringe with needles, instructions and 2 patient and practitioner labels (on the blister)
    Lidocaine No
    Volume 1.5 ml
    Country of origin Germany
    Needles 2 x 28G, 19 mm
  • Radiesse + Lidocaine (1 x 1.5 ml)

    Radiesse + Lidocaine (1 x 1.5 ml)

    £123.60

    In stock · next-day delivery

    Pack 1 x 1.5 ml syringe with 2 needles (27G, 20 mm) and a connector, instructions and 2 patient and practitioner labels (on the blister)
    Lidocaine Yes
    Volume 1.5 ml
    Country of origin Germany
    Needles 2 x 27G, 20 mm, plus connector
  • Fize PLA (analog of Sculptra)

    Fize PLA (analog of Sculptra)

    £105.99

    In stock · next-day delivery

    Korean PLA collagen stimulator, the budget-friendly alternative to Sculptra. Natural, gradual volume that lasts.

    Best zone Cheeks, temples, jawline, neck

  • Urevs 4D Fill (analog of Radiesse)

    Urevs 4D Fill (analog of Radiesse)

    £87.99

    In stock · next-day delivery

    Korean CaHA filler in the same category as Radiesse. Lift, contour and collagen stimulation at a much friendlier price.

    Best zone Jawline, chin, cheeks, nasolabial folds

  • Fize PLA+HA for Body (buttock, for example)

    Fize PLA+HA for Body (buttock, for example)

    £105.99

    In stock · next-day delivery

    Hybrid PLA and HA body filler. Instant volume from HA plus lasting collagen from PLA, designed for buttock and body contouring.

    Best zone Buttocks, hips, thighs

Choosing a collagen stimulator

Every product in this category stimulates new collagen, but they fall into three groups that behave differently in practice.

Polylactic acid (PLA): Sculptra, Fize PLA

Supplied as a powder and reconstituted before use. There is no immediate volume: the result builds gradually as new collagen forms, usually over a course of sessions. Used for global volume restoration, for example the temples, cheeks and lateral face, and for body areas.

Calcium hydroxylapatite (CaHA): Radiesse, Urevs 4D Fill

Ready-to-use gels containing CaHA microspheres. Used undiluted they give immediate structure for jawline, chin and cheek contour and keep stimulating collagen afterwards. Diluted or hyperdiluted, the volumising effect is minimal and the aim is skin quality and laxity. Read the Radiesse and hyperdilution guide.

Hybrid PLA and hyaluronic acid: Fize PLA+HA for Body

Hyaluronic acid for immediate volume plus PLA for longer-term collagen, designed for larger body areas such as the buttocks and hips.

Same material class, lower trade price

Fize PLA (polylactic acid) and Urevs 4D Fill (CaHA) use the same classes of material as Sculptra and Radiesse at a lower trade price, and both qualify for volume discounts. Urevs 4D Fill works out at £54.99 per ml against £79.20 for Radiesse. They are different products from different manufacturers, so follow each product's own instructions for use. See the side-by-side comparison.

For qualified practitioners only. Product choice, technique, dosing and aftercare follow the manufacturer's instructions and your own training. Sculptra is a trademark of Galderma. Radiesse is a trademark of Merz.

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