Collagen stimulators · Merz Aesthetics

Radiesse UK

Genuine Radiesse and Radiesse (+) from Merz at UK trade prices, dispatched from London for next-day delivery. For qualified practitioners and clinics, with no account and no minimum order.

Genuine, sealed Merz stockOrder by 1pm for next-day deliveryFree delivery from £200

Radiesse at a glance

RadiesseRadiesse (+)
MaterialCalcium hydroxylapatite (CaHA) microspheres of 25 to 45 µm in a gel carrier of sodium carboxymethylcellulose, glycerin and water
LidocaineNoYes, integrated
Pack1 x 1.5 ml syringe1 x 1.5 ml syringe
How it worksThe gel gives immediate structure. As the carrier is absorbed, the microspheres stimulate new collagen, so the result keeps developing after treatment.
Typical areasJawline, chin, cheeks and the backs of the hands. Diluted, for skin quality on the neck, décolletage and body (see below).
Trade price£118.80£123.60

Fixed trade price with no volume discount; Subscribe & save takes 1% off. Not for use in the lips.

Order Radiesse or Radiesse (+) today

Radiesse (1 x 1.5 ml)£118.80In stock, next-day delivery
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Genuine, sealed Merz stock. Order by 1pm on a weekday for next-day delivery, free from £200.

Hyperdiluted Radiesse

Dilution changes what Radiesse does. Undiluted, it lifts and contours. Mixed with saline or lidocaine, the gel becomes softer and spreads more evenly, the volumising effect fades and collagen stimulation in the skin becomes the point of the treatment. Published consensus describes two levels.

Diluted, 1:1

1.5 ml of Radiesse with 1.5 ml of diluent. Some volume plus dermal remodelling. Consensus uses it for laxity in the mid and lower face.

Hyperdiluted, 1:2 and above

1.5 ml of Radiesse with 3 ml or more of diluent. Minimal volume: the aim is firmness, elasticity and skin quality, typically on the neck, décolletage and body.

In 2024 Merz received EU approval for Radiesse to treat moderate and severe décolleté wrinkles using a 1:2 dilution with saline, based on a randomised, evaluator-blinded study in 117 patients. The US label added the same décolleté indication in 2026.

Stock Radiesse for your hyperdilution protocols

Radiesse (1 x 1.5 ml)£118.80In stock, next-day delivery
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Ratios in published consensus

AreaRatio (Radiesse : diluent)Aim
Face: cheeks and jawline1:1Mild to moderate laxity
Neck1:2 to 1:4Mild laxity, skin quality
Décolletage1:2 to 1:3 (EU indication: 1:2 with saline)Wrinkles, photodamage, mild laxity
Upper arms1:2Laxity, thin skin
Buttocks and thighs1:1 to 1:4Laxity; 1:1 or 1:2 for cellulite dimples

Sources: Goldie et al., Dermatologic Surgery 2018; de Almeida et al., Plastic and Reconstructive Surgery Global Open 2019. Apart from the EU décolleté indication, these protocols are off-label.

Preparation points from the consensus

  • Mix through a Luer lock to Luer lock connector, with at least 20 passes between the syringes so the product is evenly dispersed.
  • Inject straight away: diluted CaHA separates quickly.
  • The panel recommends that the person injecting prepares the dilution themselves.
  • Diluent: sterile 0.9% saline, lidocaine, or a mix of both. Radiesse (+) already contains lidocaine.

What you need for dilution

Luer Lock to Luer Lock Syringe Connector£2.99 or £2.69 each at 20+In stock, next-day delivery
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Saline Solution 0.9% (500 ml)£11.99 or £10.79 each at 20+In stock, next-day delivery
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The connector and the saline get an extra 3% off when you order them with Radiesse.

For qualified practitioners only. Product choice, technique, dosing and aftercare follow the manufacturer’s instructions for use and your own training and insurance.

A lower-priced CaHA: Urevs 4D Fill

Urevs 4D Fill is a Korean calcium hydroxylapatite filler, the same material class as Radiesse, at a lower trade price: £87.99 for a box of 2 x 0.8 ml (1.6 ml), which is £54.99 per ml against £79.20 per ml for Radiesse (£118.80 for 1.5 ml). That is about 31% less per ml, and unlike Radiesse it qualifies for volume discounts of up to 10%. It is a different product from a different manufacturer, not a version of Radiesse, so follow its own instructions for use.

Save about 31% per ml with Urevs 4D Fill

Urevs 4D Fill£87.99 or £79.19 each at 20+In stock, next-day delivery
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Compare Sculptra, Radiesse, Fize PLA and Urevs

Sculptra or Radiesse?

Both stimulate collagen. Radiesse gives immediate structure and suits contouring; Sculptra is reconstituted from powder and builds volume gradually over a course of sessions. Read the full comparison.

Planning gradual volume instead? Order Sculptra

Sculptra 1 vial (5 ml)£119.99 or £107.99 each at 20+In stock, next-day delivery
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Sculptra box (2 vials)£214.99 or £193.49 each at 20+In stock, next-day delivery
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Questions

Is your Radiesse genuine?

Yes. We supply genuine, sealed Merz stock, dispatched from London.

Who can buy Radiesse from Numira?

Qualified practitioners and clinics. Trade prices are public and there is no account or minimum order.

How fast is delivery?

Orders placed by 1pm on a weekday are dispatched the same day for next-day delivery in the UK. Delivery is free on orders from £200, otherwise £9.99. We also ship to Ireland for £16.

Do volume discounts apply to Radiesse?

No. Radiesse and Radiesse (+) have a fixed trade price. Subscribe & save takes 1% off.

Can Radiesse be dissolved?

No. Unlike hyaluronic acid fillers, CaHA is not broken down by hyaluronidase, so placement and dilution need to be planned with that in mind.

Ready to order Radiesse?

Radiesse (1 x 1.5 ml)£118.80In stock, next-day delivery
Add to basketAdded to basket
Luer Lock to Luer Lock Syringe Connector£2.99 or £2.69 each at 20+In stock, next-day delivery
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Genuine, sealed Merz stock dispatched from London. Order by 1pm on a weekday for next-day delivery, free from £200.

References

  1. Goldie K, Peeters W, Alghoul M, et al. Global consensus guidelines for the injection of diluted and hyperdiluted calcium hydroxylapatite for skin tightening. Dermatologic Surgery, 2018.
  2. de Almeida AT, et al. Consensus recommendations for the use of hyperdiluted calcium hydroxyapatite (Radiesse) as a face and body biostimulatory agent. Plastic and Reconstructive Surgery Global Open, 2019. PMC6467620
  3. Merz Aesthetics. EU approval of Radiesse for moderate and severe décolleté wrinkles, 2024. merzaesthetics.com
  4. Pavicic T. Calcium hydroxylapatite filler: an overview of safety and tolerability. Journal of Drugs in Dermatology, 2013. PubMed

Radiesse is a trademark of Merz. Numira is an independent supplier and is not affiliated with Merz.